Cells by Lanthanum Materials and Methods

Laa+ stimulated quiescent Swiss 3T3 and 3T6 ceils to enter the DNA-synthesizing S phase of the cell cycle. La 3+ and insulin interacted synergistically to increase DNA syn thes i s . A br ie f exposure of the cells to soluble LaCI~ optimally stimulated entry into S. La 3+ was s imi lar to A13+ in its mitogenic properties (3. Cell. Physiol. l l g , 298, 198#), but La ~+ was i0 times more potent than AI 3+.